How Hyperuricemia Leads To Gout
Hyperuricemia is a condition where there’s too much uric in your blood. The human body creates uric oxide when it breaks down certain purines, which are often found in the food you eat and the tissues you live in. When there’s too much purine in your system, uric oxide crystals (known as urate crystal) can develop in joints, tissues, fluid, and other tissues inside the body. This can cause swelling, painful inflammation, loss of mobility, and even permanent damage to your joints.
Some of the most common causes of hyperuricemia include: being overweight; high levels of animal protein such as organ meats like liver, kidney, and heart; consumption of alcohol; and consumption of gout medicines. Gout, or hyperuricemia along with other types of renal disorders, are commonly found in people that eat a lot of red meat, especially organ meats like liver. Purines are found in organ meats such as liver, kidney, and heart. When you have high levels of urates, this means that your kidneys are also filtering your blood purine levels, which further increases the risk of having hyperuricemia.
Another cause of hyperuricemia is kidney disease. Certain kidney diseases, for example, kidney stones, kidney disease caused by inflammation, or kidney disease caused by elevated uric acids can cause elevated uric enzyme levels. In addition, certain drugs, particularly some pain medications, diuretics, antidepressants, and corticosteroids, can cause elevated uric enzyme levels.
Many people don’t realize that a condition called hypoxemia can cause hyperuricemia. A low level of oxygen in the blood is what causes hyperuricemia. This condition usually happens when the kidneys or other major organs are trying to rid the bloodstream of toxins. Hypoxia can be caused by a number of factors including: chronic dehydration; trauma to the organs; dialysis; and various medical conditions.
There are many types of medications that can increase the risk of having hyperuricemia. These medications include diuretics, medication used for hyperactivity, antidepressants, anti-inflammatory medications, and gout medications. The medications that can cause hyperuricemia include the following: beta-blockers, anticoagulants, calcium channel blockers, diuretics, heparin, IDP inhibitors, NSAIDs, phenytoin, quinolone antibiotics, selenium, and tetracycline. If you are at risk for hyperuricemia and you take any of these medications, it is important that you get yourself tested.
As you can see there are multiple risk factors when it comes to hyperuricemia. The best way to treat this condition is to prevent it. The most important thing that you can do to prevent hyperuricemia is to stay away from foods that are high in purines. Some of the higher purine foods include shellfish, red meat, fish that are smoked, turkey, and dried beans. You should also limit your consumption of alcoholic beverages. Most importantly you need to get your blood levels checked regularly in order to make sure that you and your body are healthy.
More Gout Resources
- List of Vegetables Good for Gout
- Can Carrots Lower Uric Acid?
- Does Soft Drinks Like Coca Cola Increase Uric Acid?
- Foods to avoid Hyperuricemia
- How Diuretics Cause Hyperuricemia
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